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Definition - What does Cymbalta mean?

Cymbalta, manufactured and sold by Eli Lilly and Company, is a prescription medication which is a serotonin and norepinephrine reuptake inhibitor (SNRI). Cymbalta is taken to treat physical conditions such as osteoarthritis, fibromyalgia, peripheral neuropathy, and mental disorders such as general anxiety disorder and depressive disorder.

Prior to losing its patent protection in 2013, Cymbalta was a very profitable medication for Eli Lilly. Despite this loss, however, Eli Lilly has made billions of dollars selling Cymbalta in the United States. In fact, it is estimated that Cymbalta has been sold to as many as 60 million individuals since its release in 2004.

After the FDA released warnings about Cymbalta in 2012, several lawsuits were filed alleging unlawful marketing practices. In 2014, a federal judge refused to consolidate the lawsuits into a Multi-District Litigation (MDL). The cases against the Cymbalta manufacturer are now moving individually through court.

Justipedia explains Cymbalta

How Does It Work?

Millions of individuals suffer with depression and other health conditions such as osteoarthritis and fibromyalgia. Cymbalta has been used to successfully treat many of these conditions.

Cymbalta works by triggering a change in the activity of two substances within the central nervous system (Serotonin and Norepinephrine) by lowering cell's absorption ability. Serotonin is critical to mood regulation and pain perception. Norepinephrine helps monitor how a person’s body responds to stress.

Concerns About Cymbalta

In 2012, the Federal Drug Administration issued a warning about the risks associated with the discontinuation of duloxetine (Cymbalta). According to the FDA, patients who discontinued the use of the drug were at a higher risk of “dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, insomnia, anxiety, hyperhidrosis, and fatigue.”

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